Antioxidant-Glutathione

Glutathione yog polypeptide uas muaj cysteine, uas muaj nyob rau hauv feem ntau cov kab mob aerobic. Nws tsis tuaj yeem noj los ntawm kev noj zaub mov tab sis yog tsim los ntawm cov amino acids sib xws hauv lub cell. Txij li thaum pawg sulfhydryl ntawm cysteine ​​​​yog txo qis thiab tuaj yeem txo qis tom qab oxidation, glutathione muaj kev ua haujlwm antioxidant. Nyob rau hauv lub cell, glutathione yog oxidized los yog ncaj qha oxidized los ntawm ib co metabolites thiab enzymes xws li ascorbate, glutathione peroxidase, thiab glutaredoxin nyob rau hauv lub Glutathione-ascorbate voj voog (Glutathione-ascorbate voj voog). Tom qab hnov ​​​​mob nrog qee cov tshuaj oxidizing, nws tuaj yeem txo mus rau lub xeev txo los ntawm glutathione reductase (glutathione reductase). Raws li qhov pom ntawm nws cov concentration siab hauv cell thiab nws lub luag haujlwm tseem ceeb hauv lub xeev redox ntawm lub cell, glutathione yog ib qho tseem ceeb tshaj plaws ntawm cov cellular antioxidants. Hauv qee cov kab mob, glutathione yuav raug hloov los ntawm lwm cov sulfhydryl-muaj polypeptides, xws li mycothiol (AcCys-GlcN-Ins) hauv actinomycetes, thiab bacillithiol (Cys-GlcN-Ins) hauv cov kab mob gram-zoo. mal) hloov, hauv lub cev kinetic los ntawm Trypanothione (Trypanothione).