Vitamin E yog lub ntsiab lus sib sau ua ke rau 8 qhov sib txuas ua ke ntawm tocopherol thiab tocotrienol. Lawv yog cov chav kawm ntawm fat-soluble vitamins nrog antioxidant muaj nuj nqi. Ntawm cov tebchaw, vim hais tias tib neeg lub cev nyiam absorbs thiab metabolizes -tocopherol, -tocopherol muaj bioavailability zoo tshaj plaws thiab tau kawm ntau tshaj plaws.
Alpha-tocopherol tau hais tias yog qhov tseem ceeb tshaj plaws ntawm cov rog-soluble antioxidant. Nws tshem tawm cov dawb radical intermediates thiab nres cov saw loj hlob ntawm cov dawb radicals, yog li tiv thaiv cov cell membrane los ntawm kev puas tsuaj ntawm lipid peroxides uas tsim los ntawm peroxidation saw cov tshuaj tiv thaiv. Qhov tshwm sim oxidation xeev -tocopherol dawb radicals tuaj yeem ua lwm yam antioxidants xws li vitamin C, retinol lossis panthenol raug txo kom rov qab mus rau lub xeev qis thiab ua haujlwm ntxiv rau antioxidant. Cov kev tshawb fawb cuam tshuam tau pom tias -tocopherol ntau dua li dej-soluble antioxidants tuaj yeem tiv thaiv cov hlwb uas tsis muaj glutathione peroxidase 4 (GPX4) los ntawm kev tuag, thiab GPX4 yog tib lub zog paub txog Ib qho enzyme uas txo cov lipid peroxides hauv biofilms. Txoj kev tshawb no pom tau tias nws zoo ib yam nrog cov nyhuv antioxidant ntawm -tocopherol ntawm cell membranes.
Txawm li cas los xij, nws tseem tsis tau paub meej txog lub luag haujlwm thiab qhov tseem ceeb ntawm ob peb lwm cov vitamin E hauv cov teebmeem antioxidant. Txawm hais tias -tocopherol tuaj yeem hnov mob nrog cov tshuaj electrophilic mutagenic li nucleophile, thiab tocotrienol ua lub luag haujlwm tseem ceeb hauv kev tiv thaiv neurons los ntawm kev puas tsuaj, nws muaj txiaj ntsig zoo rau ntau lwm cov vitamin E tshwj tsis yog -tocopherol. Lub luag hauj lwm ntawm antioxidants tseem tsis to taub.
